SYNTHESIS AND CHARACTERIZATION OF MUC-1 FUNCTIONALIZED GOLD NANOPARTICLES

Authors

  • Cristian Tudor MATEA Department of Nanomedicine, “Octavian Fodor” Gastroenterology Institute, Cluj-Napoca, Romania. Corresponding author: teodora.mocan@umfcluj.ro. https://orcid.org/0000-0002-5036-3454
  • Teodora MOCAN Department of Physiology, "Iuliu Hatieganu" University of Medicine and Pharmacy, Cluj-Napoca, Romania; Department of Nanomedicine, Regional Institute of Gastroenterology and Hepatology, Cluj-Napoca, Romania. Email: teodora.mocan@umfcluj.ro. https://orcid.org/0000-0001-9925-0998
  • Flaviu TABARAN Department of Physiology, "Iuliu Hatieganu" University of Medicine and Pharmacy, Cluj-Napoca, Romania; Department of Nanomedicine, Regional Institute of Gastroenterology and Hepatology, Cluj-Napoca, Romania. Corresponding author: teodora.mocan@umfcluj.ro. https://orcid.org/0000-0001-5744-0451
  • Teodora POP 3rd Gastroenterology Department “Iuliu Hatieganu” University of Medicine and Pharmacy, Cluj-Napoca, Romania. Corresponding author: teodora.mocan@umfcluj.ro.
  • Ofelia MOSTEANU 3rd Gastroenterology Department “Iuliu Hatieganu” University of Medicine and Pharmacy, Cluj-Napoca, Romania. Email: ofeliamosteanu@gmail.com. https://orcid.org/0000-0002-7469-4493
  • Lucian Constantin MOCAN 3rd Surgery Clinic, “Iuliu Hatieganu” University of Medicine and Pharmacy; Department of Nanomedicine, “Octavian Fodor” Gastroenterology Institute, Cluj-Napoca, Romania. Email: mocanlucian@yahoo.com. https://orcid.org/0000-0002-7444-7978
  • Claudiu-Dragoș ZDREHUȘ 3rd Surgery Clinic “Iuliu Hatieganu” University of Medicine and Pharmacy, Cluj-Napoca, Romania. Email: czdrehus@yahoo.com. https://orcid.org/0000-0002-7333-5405

DOI:

https://doi.org/10.24193/subbchem.2018.3.10

Keywords:

gold nanoparticles, functionalization, MUC-1 peptide

Abstract

Gold nanoparticles have been functionalized with the biologically active MUC-1 peptide conjugated to KLH and the obtained bio-nanostructure was characterized using an array of techniques such as: UV-Vis and ATR-FT-IR spectroscopy, dynamic light scattering (DLS) and atomic force microscopy (AFM). A 54 nm monodisperse bio-nanostructure with high aqueous stability was obtained.

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STUDIA UBB CHEMIA, Volume 63 (LXIII), No. 3, September 2018

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Published

2018-09-28

How to Cite

MATEA, C. T. ., MOCAN, T. ., TABARAN, F. ., POP, T. ., MOSTEANU, O., MOCAN, L. C. ., & ZDREHUȘ, C.-D. . (2018). SYNTHESIS AND CHARACTERIZATION OF MUC-1 FUNCTIONALIZED GOLD NANOPARTICLES. Studia Universitatis Babeș-Bolyai Chemia, 63(3), 129–135. https://doi.org/10.24193/subbchem.2018.3.10

Issue

Volume 63, No. 3, 2018

Section

Articles

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