COMPARATIVE CHEMOMAPPING OF PHYTOCONSTITUENTS FROM DIFFERENT EXTRACTS OF GLOBE ARTICHOKE - CYNARA SCOLYMUS L.

Authors

  • Szabolcs VÍGH Institute of Agricultural Sciences, University of Nyíregyháza; Agricultural and Molecular Research Institute, Nyíregyháza, Hungary. Corresponding author: endre.mathe64@gmail.com.
  • Zoltán CZIÁKY Agricultural and Molecular Research Institute, Nyíregyháza, Hungary. Corresponding author: endre.mathe64@gmail.com. https://orcid.org/0000-0002-1846-3236
  • László Tamás SINKA Agricultural and Molecular Research Institute, Nyíregyháza, Hungary. Corresponding author: endre.mathe64@gmail.com.
  • George Ciprian PRIBAC Faculty of Medicine, “Vasile Goldiş” Western University, Arad, Romania. Email: gpribac@rdslink.ro.
  • Liana Mioara MOŞ Faculty of Medicine, “Vasile Goldiş” Western University, Arad, Romania. Email: lianamos@uvvg.ro.
  • Violeta TURCUŞ Faculty of Medicine, “Vasile Goldiş” Western University, Arad, Romania. Email: violeta_buruiana@yahoo.com. https://orcid.org/0000-0002-2595-739X
  • Judit REMENYIK Faculty of Agriculture, Food Sciences and Environmental Management, University of Debrecen, Hungary. Email: remenyik@agr.unideb.hu. https://orcid.org/0000-0003-1321-0907
  • Endre MÁTHÉ Faculty of Medicine, “Vasile Goldiş” Western University, Arad, Romania; Agricultural and Molecular Research Institute, Nyíregyháza; Faculty of Agriculture, Food Sciences and Environmental Management, University of Debrecen, Hungary. Email: endre.mathe64@gmail.com. https://orcid.org/0000-0002-9011-177X

DOI:

https://doi.org/10.24193/subbchem.2017.2.10

Keywords:

globe artichoke, Cynara scolymus, phytoconstituents, bioactive compound, LC-ESI-MS

Abstract

Artichoke (Cynara scolymus L.) is a well-known herb for its efficiency in the prevention/treatment of liver injuries, among other human chronic diseases. The aim of present study was to analyse the phytoconstituents content of aqueous and hydro-alcoholic extracts obtained from the leaves of artichoke. The chemomapping was carried out using UHPLC-ESI-MS. Several new and some known phytoconstituents were identified in the two type of extracts that have slightly different composition profiles. The newly found phytoconstituents in artichoke, plead for multiple health promoting effects that have presumably more stochastic than determinative features. Therefore, further experiments are needed using such extracts, and based on a system biology approach to clarify the complexity of beneficial effects of artichoke.

References

R.E. J.Llorach, F. Tomás-Barberan, F. Ferreres, Journal of Agricultural and Food Chemistry, 2002, 50, 3458.

F. Fratianni, M. Tucci, M. De Palma, R. Pepe, F. Nazzaro, Food Chemistry, 2007, 104, 1282.

R. Ferracane, N. Pellegrini, A. Visconti, G. Graziani, E. Chiavaro, C. Miglio, V. Fogliano, Journal of Agricultural and Food Chemistry, 2008, 56, 8601.

F. Tomás-Barberán, J.C. Espín, Journal of the Science of Food and Agriculture, 2001, 81, 853.

M. Lutz, C. Henríquez, M. Escobar, Journal of Food Composition and Analysis, 2011, 24, 49.

X. Wu, G. Beecher, J. Holden, D. Haytowitz, S. Gebhardt, R. Prior, Journal of Agricultural and Food Chemistry, 2004, 52, 4026.

B.L. Halvorsen, Carlsen M.H., Phillips K. M., Bohn S.K., Jacobs D.R., Blomhoff R. American Journal of Clinical Nutrition, 2006, 84, 95.

M. Ben Salem, H. Affes, K. Ksouda, R. Dhouibi, Z. Sahnoun, S. Hammami, K.M. Zeghal, Plant Food for Human Nutrition, 2015, 70(4),441.

M. Rondanelli, F. Monteferrario, S. Perna, M.A. Faliva, A. Opizzi, Monaldi Archives of Chest Disease, 2013, 80 (1), 17.

B. Wider, M.H. Pittler, J. Thompson-Coon, E. Ernst, The Cochrane Database of Systematic Reviews, 2013, (3):CD003335.

A.M. Mileo, D. Di Venere, C. Abbruzzese, S. Miccadei, Oxidative Medicine and Cellular Longevity, 2015, 363827.

C. Pulito, F. Mori, A. Sacconi, L. Casadei, M. Ferraiuolo, M.C. Valerio, R. Santoro, F. Goeman, A. Maidecchi, L. Mattoli, C. Manetti, S. Di Agostino, P. Muti, G. Blandino, S. Strano, Oncotarget, 2015, 6 (20), 18134.

E.N. Simsek, T. Uysal, Asian Pacific Journal of Cancer Prevention, 2013, 14 (11), 6791.

S. Vígh, C. Pribac, M. Czapár, Z. Zsvér-Vadas, L. Moş, C. Mihali, L. Cziáky, S.T. Sinka, V. Turcuş, E. Máthé, Studia Universitas Vasile Goldiş, 2016, 26 (4), 423.

I.M. Abu-Reidah, D. Arráez-Román, A. Segura-Carretero, A. Fernández-Gutiérrez, Food Chemistry, 2013, 141, 2269.

A. Moglia, S. Lanteri, C. Comino, A. Acquadro, R. de Vos, J. Beekwilder, Journal of Agricultural and Food Chemistry, 2008, 56, 8641.

M.N. Clifford, W. Zheng, N. Kuhnert, Phytochemical Analysis, 2006, 17, 384.

R. Coinu, S. Carta, P.P. Urgeghe, N. Mulinacci, P. Pinelli, F. Franconi, A. Romani, Food Chemistry, 2007, 101, 524.

R. Ferracane, N. Pellegrini, A. Visconti, G. Graziani, E. Chiavaro, C. Miglio, V. Fogliano, Journal of Agricultural and Food Chemistry, 2008, 56, 8601.

K. Schütz, E. Muks, R. Carle, A. Schieber, Journal of Agricultural and Food Chemistry, 2006, 54, 8812.

E. Azzini, R. Bugianesi, F. Romano, D. Di Venere, S. Miccadei, A. Durazzo, The British Journal of Nutrition, 2007, 97, 963.

S. Lombardo, G. Pandino, G. Mauromicale, M. Knödler, R. Carle, A. Schieber, Food Chemistry, 2010, 119, 1175.

K. Schütz, D. Kammerer, R. Carle, A. Schieber, Journal of Agricultural and Food Chemistry, 2004, 52, 4090.

N. Mulinacci, D. Prucher, M. Peruzzi, A. Romani, P. Pinelli, C. Giaccherini, F. F. Vincieri, Journal of Pharmaceutical and Biomedical Analysis, 2004, 34, 349.

G. Pandino, F.L. Courts, S. Lombardo, G. Mauromicale, G. Williamson, Journal of Agricultural and Food Chemistry, 2009, 58, 1026.

F. Piozzi, M. Paternostro, S. Passannanti, E. Gacs-Baitz, Phytochemistry, 1986, 25, 539.

K. Sas, H. Robotka, J. Toldi, L. Vécsei, Journal of the Neurological Sciences, 2007; 257 (1-2), 221.

A. Arlt, S. Sebens, S. Krebs, C. Geismann, M. Grossmann, M.L. Kruse, S. Schreiber, H. Schäfer, Oncogene, 2013, 32 (40), 4825.

L. Servillo, N. D'Onofrio, L. Longobardi, I. Sirangelo, A. Giovane, D. Cautela, D. Castaldo, A. Giordano, M.L. Balestrieri, Journal of Cellular Biochemistry, 2013, 114 (11), 2522.

R. Bernhard, Lebensmittel-Wissenschaft & Technologie, 1972, 5, 185.

M. Kawase, H. Sakagami, N. Motohashi, H. Hauer, S.S. Chatterjee, G. Spengler, A.V. Vigyikanne, A. Molnár, J. Molnár, In Vivo, 2005; 19 (4), 705.

H. Zhao, M. Zhang, F. Zhou, W. Cao, L. Bi, Y. Xie, Q. Yang, S. Wang, Journal of Molecular and Cellular Cardiology, 2016, 101,11.

J. Hinou, C. Harvala, S. Philianos, Annales Pharmaceutiques Francaises, 1989, 47 (2), 95.

M.V. Pereira Dos Santos Nascimento, F. Arruda-Silva, A.B. Gobbo Luz, B. Baratto, D. Venzke, B.G. Mendes, T.S. Fröde, M. Geraldo Pizzolatti, E.M. Dalmarco, Immunopharmacology and Immunotoxicology, 2016, 38 (5), 344.

C. Pereira, L. Barros, A.M. Carvalho, C. Santos-Buelga, I.C. Ferreira, Food and Function, 2015, 6 (1), 56.

D. Negro, V. Montesano, S. Grieco, P. Crupi, G. Sarli, A. De Lisi, G. Sonnante, Journal of Food Sciience, 2012, 77(2), C244.

J. Magielse, A. Verlaet, A. Breynaert, B. M. Keenoy, S. Apers, L. Pieters, N. Hermans, Molecular Nutrition and Food Research, 2014, 58 (1), 211.

M. Wang, J.E. Simon, I.F. Aviles, K. He, Q.Y. Zheng, Y. Tadmor, Journal of Agricultural and Food Chemistry, 2003, 51 (3), 601.

K. Patel, M. Gadewar, V. Tahilyani, D.K. Patel, Chinese Journal of Integrative Medicine, 2013, 19, 792.

J. Liu, X. Wen, B. Liu, Q. Zhang, J. Zhang, H. Miao, R. Zhu, Molecular Medicine Reports, 2016, 13 (3), 2401.

S. Noori, Z. M. Hassan, B. Yaghmaei, M. Dolatkhah, Cellular Immunology, 2013, 286 (1-2),16.

H. Shi, H. Shi, F. Ren, D. Chen, Y. Chen, Z. Duan, Journal of Cellular and Molecular Medicine, 2016, doi: 10.1111/jcmm.12994.

A. Yoshinaga, N. Kajiya, K. Oishi, Y. Kamada, A. Ikeda, P. K. Chigwechokha, T. Kibe, M. Kishida, S. Kishida, M. Komatsu, K. Shiozaki, European Journal of Pharmacoogy,. 2016, 782, 21.

S.K. Ku, J.S. Bae, Canadian Journal of Physiology and Pharmacology, 2016, 94 (3), 287.

H. Kang, S.K. Ku, B. Jung, J.S. Bae, Inflammation Research, 2015, 64(12), 1005.

M. Lutz, C. Henzíquez, M. Escobar, Journal of Food Composition and Analysis, 2011, 24, 49.

W. Li, Y. Wang, X. Wang, H. Zhang, Z. He, W. Zhi, F. Liu, X. Niu, Fundamental and Clinical Pharmacology, 2016, doi: 10.1111/fcp.12255.

I. Mokdad Bzeouich, N. Mustapha, M. Maatouk, K. Ghedira, M. Ghoul, L. Chekir-Ghedira, Regulatory Toxicology and Pharmacology, 2016, 82, 48.

K.C. Choi, Y.O. Son, J.M. Hwang, B.T. Kim, M. Chae, J.C. Lee, Pharmaceutical Biology, 2016, 55 (1), 611.

F.J. Lima, F. Cosker, T.S. Brito, H.V. Ribeiro-Filho, C.M. Silva, K.S. Aragão, S. Lahlou, M.H. Souza, A.A. Santos, P.J. Magalhães, European Journal of Pharmacology, 2014, 740, 192.

Y.Y. Chen, M.H. Lee, C.C. Hsu, C.L. Wei, Y.C. Tsai, Journal of Agricultural and Food Chemistry, 2012, 60 (4), 955.

R.S. Pawar, E. Grundel, Drug Testing and Analysis, 2016, doi: 10.1002/dta. 1980.

P. Mucaji, D. Grancai, M. Nagy, M. Budĕsínský, K. Ubik, Ceska a Slovenska Farmacie, 2001, 50 (6), 277.

H. Ding, H. Wang, L. Zhu, W. Wei, Neurochemical Research, 2016, doi:10.1007/s11064-016-2077-8.

W.T. Gai, D.P. Yu, X. S. Wang, P.T. Wang, Oncology Letters, 2016, 12 (4), 2880.

J.L. Gao, Y.M. Shui, W. Jiang, E.Y. Huang, Q.Y. Shou, X. Ji, B.C. He, G.Y. Lv, T.C. He, Oncotarget. 2016. 71802.

E. Serni, V. Audino, S. Del Carlo, C. Manera, G. Saccomanni, M. Macchia, Natural Product Research, 2013, 27 (23), 2212.

T. Kroon, T. Baccega, A. Olsén, J. Gabrielsson, N.D. Oakes, Journal of Lipid Research, 2017, 58 (1), 31.

S. Mocellin, M. Briarava, P. Pilati, Journal of the National Cancer Institute, 2016, 109 (3), pii: djw230.

S.C. Gominak, Medical Hypotheses, 2016, 94, 103.

STUDIA UBB CHEMIA, Volume 62 (LXII), No. 2, Tome I, June 2017

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Published

2017-06-01

How to Cite

VÍGH, S. ., CZIÁKY, Z. ., SINKA, L. T. ., PRIBAC, G. C. ., MOŞ, L. M. ., TURCUŞ, V. ., … MÁTHÉ, E. . (2017). COMPARATIVE CHEMOMAPPING OF PHYTOCONSTITUENTS FROM DIFFERENT EXTRACTS OF GLOBE ARTICHOKE - CYNARA SCOLYMUS L. Studia Universitatis Babeș-Bolyai Chemia, 62(2), 125–143. https://doi.org/10.24193/subbchem.2017.2.10

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Volume 62, No. 2, Tome I, 2017

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