EPR FINGERPRINTING AND ANTIOXIDANT RESPONSE OF FOUR SELECTED PLANTAGO SPECIES

Anca  FĂRCAȘ; Cezara  ZĂGREAN-TUZA; Laurian  VLASE; Ana-Maria  GHELDIU; Marcel  PÂRVU; Augustin C.  MOȚ

doi:10.24193/subbchem.2020.2.17

EPR FINGERPRINTING AND ANTIOXIDANT RESPONSE OF FOUR SELECTED PLANTAGO SPECIES

Authors

Anca FĂRCAȘ Institute of Biological Research, Babes-Bolyai University; National Institute for Research and Development of Isotopic and Molecular Technologies, Cluj-Napoca, Romania. Email: ancuta.farkas@ubbcluj.ro. https://orcid.org/0000-0002-7085-1623
Cezara ZĂGREAN-TUZA Faculty of Chemistry and Chemical Engineering, Babeş-Bolyai University, Cluj-Napoca, Romania. Corresponding author: augustinmot@chem.ubbcluj.ro. https://orcid.org/0000-0001-9971-7105
Laurian VLASE Department of Pharmaceutical Technology and Biopharmaceutics, Faculty of Pharmacy, Iuliu Hațieganu University of Medicine and Pharmacy; Department of Clinical Pharmacology and Pharmacokinetics. Corresponding author: augustinmot@chem.ubbcluj.ro. https://orcid.org/0000-0002-0664-3387
Ana-Maria GHELDIU Department of Pharmaceutical Botany, Faculty of Pharmacy, Iuliu Hațieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania. Email: anamaria.gheldiu@yahoo.com.
Marcel PÂRVU Institute of Biological Research, Babes-Bolyai University, Cluj-Napoca, Romania. Corresponding author: augustinmot@chem.ubbcluj.ro. https://orcid.org/0000-0002-4799-8387
Augustin C. MOȚ Faculty of Chemistry and Chemical Engineering, Babeş-Bolyai University; National Institute for Research and Development of Isotopic and Molecular Technologies, Cluj-Napoca, Romania. Email: augustinmot@chem.ubbcluj.ro. https://orcid.org/0000-0002-1679-0487

DOI:

https://doi.org/10.24193/subbchem.2020.2.17

Keywords:

Plantago, Antioxidants, EPR fingerprinting

Abstract

In this study we compare the phytochemical composition and antioxidant properties of four Plantago species (P. cornuti, P. lanceolata, P. major and P. media), in terms of radical scavenging ability and their reductive properties in corroboration with EPR spectroscopy profiling. We found that Plantago extracts possess very low prooxidant activity while being efficient radical scavengers and electron donors. P. media showed the strongest antioxidant activity from the four species investigated. The relative composition derived from the EPR spectra of the studied extracts was compared to the phytochemical composition determined by HPLC-MS analysis. Downhill Simplex algorithm simulation of EPR experimental signals revealed that all four Plantago extracts display luteolin and chlorogenic acid profiles, as well as quercetin glycosides, especially rutin. EPR spectroscopy appears to be a useful tool for discrimination of radical-based complex mixture, rendering it as an alternative method for predicting chemical behaviour, regardless of synergistic or antagonistic effects.

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STUDIA UBB CHEMIA, Volume 65 (LXV), No. 2, June 2020

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Published

2020-06-30

How to Cite

FĂRCAȘ, A. ., ZĂGREAN-TUZA, C. ., VLASE, L. ., GHELDIU, A.-M. ., PÂRVU, M. ., & MOȚ, A. C. . (2020). EPR FINGERPRINTING AND ANTIOXIDANT RESPONSE OF FOUR SELECTED PLANTAGO SPECIES. Studia Universitatis Babeș-Bolyai Chemia, 65(2), 209–220. https://doi.org/10.24193/subbchem.2020.2.17