BIOACTIVE POLYPHENOLIC COMPOUNDS FROM MOTHERWORT AND HAWTHORN HYDROETHANOLIC EXTRACTS

Authors

  • Andreea-Miruna NEAGU University Politehnica of Bucharest, Faculty of Applied Chemistry and Materials Science, 1-7 Gheorghe Polizu Street, district 1, RO-011061, Bucharest, Romania.
  • Corneliu-Mircea CODREANU “Dunarea de Jos” University of Galati, Faculty of Physical Education and Sport, 63-65 Garii Street, RO-800003, Galati, Romania.
  • Vasile STAICU University Politehnica of Bucharest, Faculty of Applied Chemistry and Materials Science, 1-7 Gheorghe Polizu Street, district 1, RO-011061, Bucharest, Romania; Research and Development Department, S.C. Hofigal Export-Import S.A., 2 Intrarea Serelor Street, district 4, RO-042124, Bucharest, Romania. https://orcid.org/0000-0003-4409-1146
  • Raluca STAN University Politehnica of Bucharest, Faculty of Applied Chemistry and Materials Science, 1-7 Gheorghe Polizu Street, district 1, RO-011061, Bucharest, Romania. *Corresponding author: rl_stan2000@yahoo.com https://orcid.org/0000-0002-4490-5173

DOI:

https://doi.org/10.24193/subbchem.2021.4.09

Keywords:

Hawthorn, Motherwort, reflux, percolation, maceration, polyphenols.

Abstract

Motherwort (Leonurus cardiaca) and Hawthorn (Crataegus monogyna) are known from traditional phytotherapy as being effective in alleviating many cardiovascular system disorders. This paper presents the studies made to assess the phytochemical compozition of the herbal extracts prepared from Motherwort (aerial parts), Hawthorn (fruits) and Hawthorn (flowers and leaves) by maceration, percolation and reflux using a mixture of ethanol and water as solvent. Optimum extraction conditions were evaluated for enhancing the content of the active substances (certain flavones and polyphenols: anthocyanins, etc.) present in the two studied plants, that are useful in the prevention of many cardiovascular disorders. Their chemical composition was investigated using UV-VIS spectroscopy methods: total polyphenolic content, total flavones content and the antioxidant activity were determined. The study showed that reflux extraction technique is more effective for extracting polyphenolic compounds from the two studied medicinal plants. Varying the extraction parameters led to the attainment of new phytotherapeutic extracts that are optimally beneficial in the phytotherapy of cardiovascular diseases.

References

W-T. Chang; J. Dao; Z-H. Shao; Am. J, Chin. Med., 2005, 33, 1–10.

L. Barros; A. M. Carvalho; I. C. F. R. Ferreira; Phytochem. Anal., 2011, 22, 181-188.

R. C. Fierascu; I. Fierascu; A. Ortan; I. C. Fierascu; V. Anuta; B. S. Velescu; S. M. Pituru; C. E. Dinu-Pirvu; BioMed Res. Int., 2019, 2, 1-13.

B. Sadowska; B. Micota; M. Rozalski; M. Redzynia; M. Rozalski; Innate Immun., 2017, 0, 1-10.

J. Stewart; G. Manmathan; P. Wilkinson; JR. Soc. Med. Cardiovasc. Dis., 2017, 0, 1-9.

A. Altemimi; N. Lakhssassi; A. Baharlouei; D. G. Watson; D. A. Lightfoot; Plants, 2017, 42, 1-23.

Hawthorn leaf and flower, Crataegus spp., folium cum flore; European Medicines Agency, 2016, 268358.

M. L. McCullough; J. J. Peterson; R. Patel; P. F. Jacques; R. Shah; J. T. Dwyer; Am. J. Clin. Nutr., 2012, 95, 454-464.

ISO 14502-1:2005(E), Determination of substances characteristic of green and black tea – Part 1: Content of total polyphenols in tea – Colorimetric method using Folin-Ciocalteu reagent.

L. Silva; B. Pezzini; L. Soares; Pharmacogn. Mag., 2015, 11, 96-101.

Bilberry Fruit, fresh, Monograph, in European Pharmacopoeia, 2017, I, 1173.

R. Apak; K. Güçlü; M. Özyürek; S. Esi ̇n Karademi ̇r; M. Altun; Free Radic. Res., 2005, 39, 949-961.

STUDIA UBB CHEMIA, Volume 66 (LXVI), No. 4, December 2021

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Published

2021-12-30

How to Cite

NEAGU, A.-M., CODREANU, C.-M., STAICU, V., & STAN, R. (2021). BIOACTIVE POLYPHENOLIC COMPOUNDS FROM MOTHERWORT AND HAWTHORN HYDROETHANOLIC EXTRACTS. Studia Universitatis Babeș-Bolyai Chemia, 66(4), 123–132. https://doi.org/10.24193/subbchem.2021.4.09

Issue

Volume 66, No. 4, 2021

Section

Articles

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Copyright (c) 2021 Studia Universitatis Babeș-Bolyai Chemia

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This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

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