CHEMICAL CHARACTERIZATION AND DETERGENT POTENTIAL OF CHELIDONIUM MAJUS EXTRACTS

Anca BECZE; Dorina SIMEDRU; Liviu BÎLTEANU; Paul UIUIU

doi:10.24193/subbchem.2025.2.04

CHEMICAL CHARACTERIZATION AND DETERGENT POTENTIAL OF CHELIDONIUM MAJUS EXTRACTS

Authors

Anca BECZE National Institute for Research and Development of Optoelectronics INOE 2000, Research Institute for Analytical Instrumentation, 67 Donath Str., RO-400293 Cluj-Napoca, Romania. *Corresponding author: anca.naghiu@icia.ro https://orcid.org/0000-0003-1418-689X
Dorina SIMEDRU National Institute for Research and Development of Optoelectronics INOE 2000, Research Institute for Analytical Instrumentation, 67 Donath Str., RO-400293 Cluj-Napoca, Romania https://orcid.org/0000-0003-4914-6986
Liviu BÎLTEANU BEST CLEAN EUROPE LtD., located in Florești, Cluj County, Romania https://orcid.org/0000-0002-3781-2892
Paul UIUIU Department of Fundamental Sciences, Faculty of Animal Science and Biotechnologies, University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca, 3-5 Mănăştur Street, RO-400372 Cluj-Napoca, Romania https://orcid.org/0000-0002-6835-3414

DOI:

https://doi.org/10.24193/subbchem.2025.2.04

Keywords:

Chelidonium majus, accelerated solvent extraction, ultrasound-assisted extraction, alkaloids, flavonoids, polyphenols, antimicrobial activity, antioxidant capacity, extraction efficiency

Abstract

The present study investigates the impact of different extraction methods—accelerated solvent extraction (ASE), ultrasound-assisted extraction (UAE), and maceration on the yield, phytochemical composition, antioxidant activity, and antimicrobial potential of Chelidonium majus extracts. ASE demonstrated the highest extraction yield (85.7%) and alkaloid content (5.4 mg AE/ml), correlating with enhanced antimicrobial activity against Escherichia coli, Staphylococcus aureus, and Candida albicans (lowest MIC values: 3.12%, 2.50%, and 6.25%, respectively). UAE resulted in the highest polyphenol content (15.2 mg GAE/ml) and antioxidant capacity (12.8 ± 1.5 µmol Trolox/ml), suggesting its effectiveness in preserving antioxidant compounds. Maceration produced the lowest bioactive compound yield and biological activity. These findings indicate that ASE is optimal for antimicrobial applications, while UAE is preferable for antioxidant-enriched extracts. The results provide valuable insights for optimizing C. majus extraction in pharmaceutical, food, and cosmetic formulations.

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STUDIA UBB CHEMIA, Volume 70 (LXX), No. 2, June 2025

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Published

2025-06-20

How to Cite

BECZE, A., SIMEDRU, D., BÎLTEANU, L., & UIUIU, P. (2025). CHEMICAL CHARACTERIZATION AND DETERGENT POTENTIAL OF CHELIDONIUM MAJUS EXTRACTS. Studia Universitatis Babeș-Bolyai Chemia, 70(2), 53–65. https://doi.org/10.24193/subbchem.2025.2.04