ENTRAPMENT OF LIPASE B FROM CANDIDA ANTARCTICA IN TAILORED SOL-GEL MATRICES FOR THE SYNTHESIS OF BENZYL DECANOATE – IMPORTANCE OF USING AN ADDITIVE
DOI:
https://doi.org/10.24193/subbchem.2023.3.08Keywords:
benzyl decanoate, esterification, solvent free system, lipase, additive, sol-gel, biocatalysis, aroma esterAbstract
Benzyl decanoate was successfully synthesized by the direct esterification of decanoic acid with benzyl alcohol mediated by lipase B from Candida antarctica immobilized by entrapment in a sol-gel matrix in a solvent-free system, using a ternary mixture of silane precursors and glycerol as additive. The most active (LS-6, 92.1% conversion after 90 minutes) and stable biocatalyst (95% of the initial activity after 7 reaction cycles) yielded 2.2 g of benzyl decanoate in a scaled-up process (91% isolation yield).
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