ENTRAPMENT OF LIPASE B FROM CANDIDA ANTARCTICA IN TAILORED SOL-GEL MATRICES FOR THE SYNTHESIS OF BENZYL DECANOATE – IMPORTANCE OF USING AN ADDITIVE
DOI:
https://doi.org/10.24193/subbchem.2023.3.08Keywords:
benzyl decanoate, esterification, solvent free system, lipase, additive, sol-gel, biocatalysis, aroma esterAbstract
Benzyl decanoate was successfully synthesized by the direct esterification of decanoic acid with benzyl alcohol mediated by lipase B from Candida antarctica immobilized by entrapment in a sol-gel matrix in a solvent-free system, using a ternary mixture of silane precursors and glycerol as additive. The most active (LS-6, 92.1% conversion after 90 minutes) and stable biocatalyst (95% of the initial activity after 7 reaction cycles) yielded 2.2 g of benzyl decanoate in a scaled-up process (91% isolation yield).
References
I. C. Perdomo; S. G. A. Pinto; D. Romano; M. L. Contente; F. Paradisi; F. Molinari; J. Agric. Food Chem.; 2019; 67; 6517−6522
A. G. A. Sa; A. C. de Meneses; P. H. H. de Araujo; D. de Oliveira; Trends Food Sci. Technol.; 2017; 69; 95-105
R. Semproli; S. N. Chanquia; J. P. Bittner; S. Muller; P. D. de Maria; S. Kara; D. Ubiali; ACS Sustainable Chem. Eng.; 2023; 11; 5926-5936
B. Lorenzo; L. Fernandez; J. Ortega; L. Dominguez; Processes; 2023; 11; 1640
K. P. Dhake; D. D. Thakare; B.M. Bhanage; Flavour Fragr. J.; 2013; 28; 71-83
A. I. Dudu; L. C. Bencze; C. Paizs; M. I. Toșa; React. Chem. Eng.; 2022; 7. 442-449
M. T. Reetz; A. Zonta; J. Simpelkamp; Biotechnol. Bioeng.; 1996; 49; 527-534
M. E. Moisă; C. G. Spelmezan; C. Paul; J. H. Bartha-Vari; L. C. Bencze, F. D. Irimie; C. Paizs, M. I. Toșa; RSC Adv.; 2017; 7; 52977-52987
S. Serra; C. Fuganti; E. Brenna; Trends Biotechnol.; 2005; 23; 193-198
A. I. Dudu; M. A. Lăcătuș; L. C. Bencze; C. Paizs; M. I. Toșa; ACS Sustainable Chem. Eng.; 2021; 9; 5461-5469
D. A. Sanchez; G. M. Tonetto; M. L. Ferreira; Catalysts; 2023; 13; 473
J. Zheng; X. Fu; X. Ying; Y. Zhang; Z. Wang; Anal. Biochem.; 2014; 452; 13-15
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