BEHAVIOR OF MULTISUBSTITUTED HYDROXYAPATITES IN WATER AND SIMULATED BODY FLUID

Oana CADAR; Reka  BALINT; Gheorghe  TOMOAIA-COTISEL; Diana Alexandra  FLOREA; Ioan PETEAN; Aurora MOCANU; Ossi HOROVITZ

doi:10.24193/subbchem.2017.4.23

BEHAVIOR OF MULTISUBSTITUTED HYDROXYAPATITES IN WATER AND SIMULATED BODY FLUID

Authors

Oana CADAR Research Institute for Analytical Instrumentation (INCDO-INOE 2000), Cluj-Napoca, Romania. Email: oana.cadar@icia.ro. https://orcid.org/0000-0002-0879-9211
Reka BALINT Research Center of Physical Chemistry, Faculty of Chemistry and Chemical Engineering, Babeş-Bolyai University, Cluj-Napoca, Romania. Email: reka.balint@ubbcluj.ro. https://orcid.org/0000-0003-2395-116X
Gheorghe TOMOAIA-COTISEL Department of Orthopedics and Traumatology, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca; Academy of Romanian Scientists, Bucharest, Romania. Email: tomoaia2000@yahoo.com. https://orcid.org/0000-0002-5633-6895
Diana Alexandra FLOREA Department of Chemical Engineering, Faculty of Chemistry and Chemical Engineering, Babeş-Bolyai University, Cluj-Napoca, Romania. Email: diana_florea03@yahoo.com. https://orcid.org/0000-0003-4054-972X
Ioan PETEAN Department of Chemical Engineering, Research Center in Physical Chemistry, Faculty of Chemistry and Chemical Engineering, Babeş-Bolyai University, Cluj-Napoca, Romania. Email: petean@chem.ubbcluj.ro. https://orcid.org/0000-0003-3274-8817
Aurora MOCANU Research Center of Physical Chemistry, Faculty of Chemistry and Chemical Engineering, Babeş-Bolyai University, Cluj-Napoca, Romania. Email: aurora.mocanu@ubbcluj.ro. https://orcid.org/0000-0002-8728-045X
Ossi HOROVITZ Research Center of Physical Chemistry, Faculty of Chemistry and Chemical Engineering, Babeş-Bolyai University, Cluj-Napoca, Romania. Corresponding author: mocanu.aurora@gmail.com. https://orcid.org/0000-0002-3652-8558

DOI:

https://doi.org/10.24193/subbchem.2017.4.23

Keywords:

multisubstituted hydroxyapatites, magnesium, zinc, strontium, silicon, ions release, water, SBF

Abstract

Nanostructured hydroxyapatite (HAP) and three multiple substituted HAPs, containing Mg, Zn, Sr and Si were synthesized by a wet precipitation method. The presence of the HAP lattice as unique crystalline phase was established by XRD and by FTIR spectroscopy. The chemical composition was confirmed by SEM-EDX. The TEM, SEM and AFM imaging showed the morphology of these biomaterials. The elements release in water and in simulated body fluid (SBF) was monitored in time, from 1 to 90 days, by using inductively coupled plasma optical emission spectrometry (ICP-OES). The results are important for the future use of these hydroxyapatite biomaterials, as bone substitutes or coatings on metallic implants, able to release essential physiological elements, both in vitro and in vivo, with great impact in orthopedics and dentistry.

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STUDIA UBB CHEMIA, Volume 62 (LXII), No. 4, Tome II, June 2017

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Published

2017-12-29

How to Cite

CADAR, O., BALINT, R. ., TOMOAIA-COTISEL, G. ., FLOREA, D. A. ., PETEAN, I., MOCANU, A., & HOROVITZ, O. (2017). BEHAVIOR OF MULTISUBSTITUTED HYDROXYAPATITES IN WATER AND SIMULATED BODY FLUID. Studia Universitatis Babeș-Bolyai Chemia, 62(4, Tome II), 269–281. https://doi.org/10.24193/subbchem.2017.4.23