ANTIMICROBIAL ACTIVITY AND CHEMICAL COMPOSITION OF TWO EXPERIMENTAL GELS BASED ON ESSENTIAL OILS

Laura Monica  DASCALU (RUSU); Marioara  MOLDOVAN; Doina  PRODAN; Irina  CIOTLAUS; Rahela  CARPA; Razvan  ENE; Sorina  SAVA; Radu  CHIFOR; Mindra Eugenia  BADEA

doi:10.24193/subbchem.2020.2.05

ANTIMICROBIAL ACTIVITY AND CHEMICAL COMPOSITION OF TWO EXPERIMENTAL GELS BASED ON ESSENTIAL OILS

Authors

Laura Monica DASCALU (RUSU) Assistant Lecturer PhD, Department of Prosthodontics and Dental Materials, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania. Email: dascalu.monica@umfcluj.ro. https://orcid.org/0000-0001-5191-6738
Marioara MOLDOVAN Research Engineeer PhD, Department of Polymer Composites, Babes-Bolyai University, Raluca Ripan Institute of Chemistry, Cluj-Napoca, Romania. Email: iccrr@ubbcluj.ro. https://orcid.org/0000-0001-9714-4809
Doina PRODAN Research Engineeer PhD, Department of Polymer Composites, Babes-Bolyai University, Raluca Ripan Institute of Chemistry, Cluj-Napoca, Romania. Email: iccrr@ubbcluj.ro. https://orcid.org/0000-0003-2467-2453
Irina CIOTLAUS Research Engineeer PhD, Organic Compounds Laboratory, Department of Polymer Composites, Babes-Bolyai University, Raluca Ripan Institute of Chemistry, Cluj-Napoca, Romania. Email: iccrr@ubbcluj.ro. https://orcid.org/0000-0002-9012-7747
Rahela CARPA Department of Molecular Biology and Biotechnology, Faculty of Biology and Geology, Babeș Bolyai University, Cluj-Napoca, Romania. Email: rahela.carpa@ubbcluj.ro. https://orcid.org/0000-0001-8974-1718
Razvan ENE Dr. MD, Orthopedics and Traumatology Department, Carol Davila University of Medicine and Pharmacy, Bucharest; Bucharest Emergency University Hospital, Romania. Corresponding author: savasorina@yahoo.com. https://orcid.org/0000-0002-8866-7699
Sorina SAVA Department of Prosthodontics and Dental Materials, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania. Email: savasorina@yahoo.com. https://orcid.org/0000-0001-8658-1384
Radu CHIFOR Department of Preventive Dental Medicine, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania. Email: chifor.radu@umfcluj.ro. https://orcid.org/0000-0002-8262-2166
Mindra Eugenia BADEA Department of Preventive Dental Medicine, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania. Email: mebadea@umfcluj.ro. https://orcid.org/0000-0003-3136-6956

DOI:

https://doi.org/10.24193/subbchem.2020.2.05

Keywords:

GC-MS, SEM, antibacterial effect

Abstract

In this study, the comparative testing of the antimicrobial efficacy of 2 experimental photosensitizers (PS-H; PS-T) based on natural compounds with a commercial one based on toluidine blue O (TBO) FotoSan® was performed, by antimicrobial tests with G- and G+ bacterial strains and through SEM microscopy on dental enamel, using LED phototherapy. For the formulation of the experimental natural photosensitizers we used Frankincense (T) and Thieves (H) essential oils (EO), used as photosensitizing agents in antimicrobial photodynamic therapy in the control of the microbial biofilm of the oral cavity. We also tested the composition of experimental photosensitizers by GC-MS chromatography. Our results suggest that EO should be further investigated as a promising source of natural compounds that can be used to combat bacterial strains. Essential oils can inhibit growth of a broad range of pathogens correlating to their presence in aromatic plants.

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STUDIA UBB CHEMIA, Volume 65 (LXV), No. 2, June 2020

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Published

2020-06-30

How to Cite

DASCALU (RUSU), L. M. ., MOLDOVAN, M. ., PRODAN, D. ., CIOTLAUS, I. ., CARPA, R. ., ENE, R. ., … BADEA, M. E. . (2020). ANTIMICROBIAL ACTIVITY AND CHEMICAL COMPOSITION OF TWO EXPERIMENTAL GELS BASED ON ESSENTIAL OILS. Studia Universitatis Babeș-Bolyai Chemia, 65(2), 57–67. https://doi.org/10.24193/subbchem.2020.2.05