SYNTHESIS OF NEW BENZOTHIAZOLYL-PHENOTHIAZINE DERIVATIVES

Balasz  BRÉM; Emese  GÁL; Castelia  CRISTEA; Luiza  GĂINĂ; Adriana  GROZAV; Valentin  ZAHARIA; Luminiţa  SILAGHI-DUMITRESCU

SYNTHESIS OF NEW BENZOTHIAZOLYL-PHENOTHIAZINE DERIVATIVES

Authors

Balasz BRÉM Faculty of Chemistry and Chemical Engineering, Babeş-Bolyai University, Cluj-Napoca, Romania. Email: bbrem@chem.ubbcluj.ro. https://orcid.org/0000-0001-6091-5817
Emese GÁL Faculty of Chemistry and Chemical Engineering, Babeş-Bolyai University, Cluj-Napoca, Romania. Email: emese.gal@ubbcluj.ro. https://orcid.org/0000-0003-4324-0787
Castelia CRISTEA Faculty of Chemistry and Chemical Engineering, “Babeș-Bolyai” University, Cluj-Napoca, Romania. Email: castelia.cristea@ubbcluj.ro. https://orcid.org/0000-0003-1138-2596
Luiza GĂINĂ Faculty of Chemistry and Chemical Engineering, Babeş-Bolyai University, Cluj-Napoca, Romania. Email: gluiza@chem.ubbcluj.ro. https://orcid.org/0000-0002-1328-0107
Adriana GROZAV Faculty of Pharmacy, “Iuliu Hațieganu” University of Medicine and Pharmacy, Cluj-Napoca, Romania. Email: adriana.ignat@umfcluj.ro. https://orcid.org/0000-0001-5800-0896
Valentin ZAHARIA Department of Organic Chemistry, “Iuliu Hațieganu” University of Medicine and Pharmacy, Cluj-Napoca, Romania. Email: vzaharia@umfcluj.ro. https://orcid.org/0000-0001-7083-7680
Luminiţa SILAGHI-DUMITRESCU Faculty of Chemistry and Chemical Engineering, Babeş-Bolyai University, Cluj-Napoca, Romania. Email: lusi@chem.ubbcluj.ro. https://orcid.org/0000-0001-8800-4839

Keywords:

phenothiazine, benzothiazole, NMR

Abstract

A series containing 1-, 2-, 3- and 4-(benzothiazol-2yl)-10Hphenothiazine derivatives was advantageously prepared by the condensation of each corresponding phenothiazine-carbaldehyde regioisomer with 2-amino-benzenethiol. The reaction conditions were optimized and the structures of the new compounds were unambiguously assigned based on high resolution nuclear magnetic resonance spectroscopy and mass spectrometry.

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STUDIA UBB CHEMIA, Volume 60 (LX), No. 2, June 2015

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Published

2015-06-30

How to Cite

BRÉM, B. ., GÁL, E. ., CRISTEA, C. ., GĂINĂ, L. ., GROZAV, A. ., ZAHARIA, V. ., & SILAGHI-DUMITRESCU, L. . (2015). SYNTHESIS OF NEW BENZOTHIAZOLYL-PHENOTHIAZINE DERIVATIVES. Studia Universitatis Babeș-Bolyai Chemia, 60(2), 371–378. Retrieved from https://studia.reviste.ubbcluj.ro/index.php/chemia/article/view/8457