Gc-Ms and Hplc Chromatographic Profile of Majority Volatile and Phenolic Compounds of Some Medicinal Plants From Romania

Authors

DOI:

https://doi.org/10.24193/subbchem.2024.1.08

Keywords:

medicinal plants, volatile organic compounds (VOCs), phenolic compounds, HS-SPME-GC-MS, HPLC-UV/VIS

Abstract

This study reports the identification of volatile organic compounds (VOCs) and the phenolic composition for these medicinal plants: lemon balm (Melissa officinalis), lavender (Lavandula angustifolia), and elderflower (Sambucus nigra). The HS-SPME-GC-MS hyphenated technique was used to investigate the volatiles from the three plants in fresh and dried forms. The essential oils were obtained by hydrodistillation technique, followed by GC-MS analysis. Additionally, HPLC-UV/VIS detection was used to identify the phenolic compounds of these plants. The majority compounds identified in the fresh, dried and oil of lemon balm were Z-beta-ocimene, citronellal, citronellol, b-caryophyllene, (E)-citral, (Z)-citral and geraniol respectively. The aerial part of lavender contains mainly linalool, linalyl acetate, beta-myrcene, trans-beta-ocimene, lavandulyl acetate and caryophyllene. The most compounds identified in the fresh flowers of elderflower were linalool, cis-beta-ocimene, linalool oxide (II) pyran, cis-3-hexenyl isovalerate, while in the dry flowers the majority compounds were linalool oxide (II) pyran, cis-3-hexenyl isovalerate and hexenyl tiglate. The essential oil was rich in n-hexadecanoic acid, linoleic acid, and heneicosane. Majority phenolic compounds identified in the analysed species were vanillic, sinapic, ferulic, and p-coumaric acids, while the predominant flavonoids were rutin, quercetin and epicatechin. The profile of VOCs represents an indicator in the valorisation of medicinal plants.

References

A. K. Garg; M. Faheem; S. Singh; Asian J. Plant Sci., 2021, 11, 19–21

Kavita; N. Singh; O. P. Sharma; World J. Pharm. Res., 2022, 8, 197–199

S. Miraj; N. Azizi; S. Kiani; Pharm. Lett., 2016, 8, 229–237

L. S. Muntean; M. Tămaş; S. Muntean; L. Muntean; M. M. Duda; D. I. Vârban, S. Florian; Tratat de plante medicinale cultivate şi spontane (Book with Cultivated and Spontaneous Medicinal Plants), 2nd edition, Risoprint Publishing House, Cluj-Napoca, ISBN 978-973-53-1873-4, 2016, pp. 431

W. Zam; C. Quispe; J. Sharifi-Rad; M. D. López, M. Schoebitz, M. Martorell; F. Sharopov; P. V. T. Fokou; A. P. Mishra; D. Chandran; M. Kumar; J. T. Chen; R. Pezzani; Front. Biosci. (Schol. Ed.), 2022, 14, 1–15

J. Ghazizadeh; S. Sadigh-Eteghad; W. Marx; A. Fakhari; S. Hamedeyazdan; M. Torbati; S. Taheri-Tarighi; M. Araj-Khodaei; M. Mirghafourvand; Phytother. Res., 2021, 35, 6690–6705

A. Sentkowska; M. Biesaga; K. Pyrzynska; Int. J. Food Prop., 2015, 18, 2009–2014

Z Jalal; Y. El. Atki; B. Lyoussi; A. Abdellaoui; Asian Pac. J. Trop. Biomed., 2015, 5, 458–461

G. Petrisor; L. Motelica; L. N. Craciun; O. C. Oprea; D. Ficai; A. Ficai; Int. J. Mol. Sci., 2022, 23, 3591, 1–25

A. Shakeri; A. Sahebkar; A. Abolfazl; B. Javadi; J. Ethnopharmacol., 2016, 188, 204–228

A. S. Shawl; T. Kumar; S. Shabir; N. Chishti; Z. A. Kaloo; Indian Perf., 2005, 49, 235–238

T. Costea; A. M. Străinu; C. E. Gîrd; Studia Univ. VG, SSV, 2019, 29, 159–167

R. Prusinowska; K. B. Śmigielski; Herba Pol., 2014, 60, 57–66

E. Kozuharova; V. Simeonov; D. Batovska; C. Stoycheva; H. Valchev; N. Benbassat; Pharmacia, 2023, 70, 395–403

M. Bogdan; S. Bungau; D. M. Tit; L. Copolovici; T. Behl; P. Otrisal; L. Aleya; G. Cioca; D. Berescu; D. Uivarosan; D. M. Copolovici; Rev. Chim. (Bucharest), 2020, 71, 307–315

L. Hui; L. He; L. Huan; L. Xiaolan; Z. Aiguo; Afr. J. Microbiol. Res., 2010, 4, 309

N. Dobros; K. D. Zawada; K. Paradowska; Molecules, 2023, 28, 256

C. Jianu; G. Pop; A. T. Gruia; F. G. Horhat; Int. J. Agric. Biol., 2013, 15, 772‒776

P. Singh; H. Andola; M. S. M. Rawat; G. J. Pant; J. S. Jangwan; J. Nat. Prod., 2015, 5, 268–272

A. C. Aprotosoaie; E. Gille; A. Trifan; V. S. Luca; A. Miron; Phytochem. Rev, 2017, 16, 761–799

E. Broșteanu; E. D. Hurjui; J. Hortic. For. Biotech., 2017, 21, 62–67

M. Šoškić; D. Bojović; V. Tadic; Studia UBB Chemia, 2016, 56, 127–136

M. Popescu; D. Puiu; M. Mihalache; N. Bordei; A. D. Raiciu; I. Cristea; T. Galaon; L. F. Pascu, International Symposium “The Environment and The Industry”, 2017, Proceedings Book, 206–212

E. Danila; D. A. Kaya; M. Patrascu; M. A. Kaya; S. Kumbakisaka; Rev. Chim. (Bucharest), 2018, 69; 2240–2244

N. Dobros; K. Zawada; K. Paradowska; Antioxidants, 2022, 11, 1–16

G. Stanciu; F. Aonofriesei; S. Lupsor; A. Popescu; R. Sirbu; Rev. Chim. (Bucharest), 2019, 70, 1800–1804

M. Mahboubi; Adv. Tradit. Med., 2021, 21, 405–414

J. R. Santin; L. Benvenutti; M. F. Broering; R. Nunes; F. C. Goldoni; Y. B. K. Patel; J. A Souza; M. A. T. Kopp; P. Souza; R. Cassia; V. Silva; M. V. D. Pastor; A. B. Souza; L. D. Testoni; A. G. Couto; T. M. B. Bresolin; N. L. M. Quintao; J. Ethnopharmacol., 2022, 283, 1–14

M. D. Vujanović; S. D. Đurović; M. M. Radojković; Acta Period. Technol., 2021, 52, 229–237

P. Ferreira-Santos; H. Badim; Â. C. Salvador; A. J. D. Silvestre; S. A. O. Santos; S. M. Rocha; A. M. Sousa; M. O. Pereira; C. P. Wilson; C. M. R. Rocha; J. A. Teixeira; C. M. Botelho; Biomolecules, 2021, 11, 1–22

A. Laurutis; J. Liobikas; M. Stanciauskaite; M. Marksa; K. Ramanauskiene; D. Majiene; Pharmaceutics, 2022, 14, 1–15

A. Oniszczuk; M. Olech; T. Oniszczuk; K. Wojtunik-Kulesza; A. Wójtowicz; Arab. J. Chem., 2019, 12, 4719–4730

C. Bitwell; S. S. Indra; C. Lukec; M. K. Kakoma; Sci. African., 2023, 19, 1–20

R. Kant; A. Kumar; Sustain. Chem. Pharm., 2022, 30, 1–20

A. A. Mohamed; B. M. Alotaibi; J. Umm Al-Qura Univ. Appl. Sci., 2023, 9, 40–49

A. Iordache; M. Culea; C. Gherman; O. Cozar; Nucl. Instrum. Methods Phys. Res., 2009, 267, 338–342

J. D. Lozada-Ramírez; A. E. Ortega-Regules; L. R. Hernández; C. A. de Parrodi; Appl. Sci., 2021, 11, 1–24

J. Zhao; M. Wang; S. G. Saroja; I. A. Khana; J. Pharm. Biomed. Anal., 2021, 207, 1–27

E. P. Siqueira; T M. A. Alves; C. L. Zani; Rev. Bras. Farmacogn., 2007, 17, 565–571

F. Belliardo; C. Bicchi; C. Cordero; E. Liberto; P. Rubiolo; B. Sgorbini; J. Chromatogr. Sci., 2006, 44, 416–429

M. Ibrahim; M. Agarwal; G. Hardy; Y. Ren; J. Biosci. Med., 2017, 5, 13–31

L. M. Dascalu (Rusu); M. Moldovan; D. Prodan; I. Ciotlaus; R. Carpa; R. Ene; S. Sava; R. Chifor; M. E. Badea; Studia UBB Chemia, 2020, 65, 57–67

S. M. C. Mureșan; A. Dreanca; C. Repciuc; C. Dejescu; O. Rotar; R. A. Pop; S. Pantea; E. Pall; I. Ciotlaus; C. Sarosi; A. G. Mohan; M. Moldovan; L. Oana; Appl. Sci., 2023, 13, 1–20

H. Yu; C. Zhang; Y. Xie; J. Mei, J. Xie; Membranes, 2022, 12, 1–14

A. Wesołowska; P. Jadczak; D. Kulpa; W. Przewodowski; Molecules, 2019, 24, 1–13

G. Farré-Armengol; I. Filella; J. Llusià; J. Peñuelas; Molecules, 2017, 22,1-9.

S.-U. Rehman; R. Latief; K. A. Bhat; M. A. Khuroo; A. S. Shawl; S. Chandra; Arab. J. Chem., 2017, 10, S2 485–S2 490

F. Ieri; L. Cecchi; P. Vignolini; M. F. Belcaro; A. Romani; Adv. Hort. Sci., 2017 31, 141–147

Ö. Çelebi; H. Fidan; I. Ilie; N. Petkova; I. Dincheva; V. Gandova; S. Stankov;

A. Stoyanova; Turk. J. Agric. For., 2023, 47, 67-78

F. Abdellatif; H. Boudjella; A. Zitouni; A. Hassani; EXCLI J., 2014, 13, 772–781

A. A. Taherpour; H. Maroofi; Z. Rafiea; K. Larijani; Nat. Prod. Res., 2012, 26, 152–160

J. Sharifi-Rad; C. Quispe; J. Herrera-Bravo; M. Akram; W. Abbaass; P. Semwal; S. Painuli; D. A. Konovalov; M. A. Alfred; N. V. A. Kumar; M. Imran; M. Nadeem; B. Sawicka; P. Pszczółkowski; B. Bienia; P. Barbaś; S. Mahmud; A. Durazzo; M. Lucarini; A. Santini; M. Martorell; D. Calina; Hindawi, Oxid. Med. Cell. Longev., 2021, 2021, 1–20

B. Cosge; A. Ipek; B. Gurbuz; J. Appl. Biol. Sci., 2009, 3, 149–152

M. Kazemi; F. Esmaili; J. Biol. Environ. Sci., 2014, 8, 111–113

M. Hanceanu; A. C. Aprostoaie; E. Gille; A. Poiata; C. Tuchilus; A. Spac;

U. Stanescu; Rev. Med. Chir. Soc. Med. Nat., 2008, 112, 843-847

C. Da Porto; D. Decorti; Planta Med., 2008, 74, 182–187

F. U. Afifi; R. Abu-Dahab; S. Beltran; B. B. Alcade; I. F. Abaza; Arab. J. Med. Aromat. Plants., 2016, 2, 71–85

I. R. Suica-Bunghez; R. M. Senin; R. Stoica; Biol. Life. Sci. Forum., 2022, 20,

–15

T. Zagorcheva; S. D. Stanev; K. Rusanov; I. Atanassov; J. Agri. Sci. Technol., 2013, 5, 459–462

J. Fu; J. Zhao; Y. Zhu; J. Tang; Food Anal. Methods, 2017, 10, 2373–2382

M. Torabbeigi; P. Aberoomand Azar; Acta Chromatogr., 2013, 3, 571–579

G. E. S. Batiha; J. O. Teibo; L. Wasefet; H. M. Shaheen; A. P. Akomolafe; T. K. A. Teibo; M. Al‑K. Hayder; A. I. Al-Garbeeb; A. Alexiou; M. Papadakis; Naunyn-Schmiedeberg's Arch. Pharmacol., 2023, 396, 877–900

Â. C Salvador; A. J Silvestre; S. M. Rocha; Food Chem., 2017, 229, 276–285

K. R. Uhl; A. E. Mitchell; ACS Food Sci. Technol., 2022, 2, 1535–1545

H. G. Ağalar; B. Demirci; F. Demirci; N. Kırımer; Rec. Nat. Prod., 2017, 11, 491–496

A. Hajdari; N. Kelmendi; G. Mustafa; B. Mustafa; D. Nebija; Sci. World J., 2022, 2022, Article ID 2594195, 10 pages

M. Szymañski; M. Dudek-Makuch; E. Witkowska-Banaszczak; W. Bylka; A. Szymañski; Pharm. Chem. J., 2020, 54, 496–503

T. Bajer; P. Bajerová; K. Ventura; Nat. Prod. Commun., 2017, 12, 1937–1942

N. Harbourne; E. Marete; J. C, Jacquier; D. O'Riordan; 'LWT Food Sci. Technol., 2009, 42, 1468–1473

I. Pereira; P. Severino; A. C. Santosa; A. M. Silva; E. B. Souto; Colloids Surf. B: Biointerfaces, 2018, 171, 566–578

V. M. Linck; A. L. da Silva; M. Figueiro; E. B. Caramao; P. R. H. Moreno;

E. Elisabetsky; Phytomedicine, 2010, 17, 679–683

M. Miyashita; Y. Sadzuka; Food Chem. Toxicol., 2013, 53, 174–179

F. N. Souto-Maior; F. L. de Carvalho; L. C. S. L. de Morais; S. M. Netto; D. P. de Sousa; R. N. de Almeida; Pharmacol. Biochem. Behav., 2011, 100, 259–263

P. L. Santos; J. P. S. C. F. Matos; L. Picot; J. R. G. S. Almeida; J. S. S. Quintans; L. J. Quintans-Júnior; Food Chem. Toxicol., 2019, 123, 459–469

T. Ganesan; M. Subban; L. D. B. C. Leslee; S. B. Kuppannan; P. Seedevi; Biomass Convers. Biorefinery, 2022, 1–12

C. Ji Zheng; J.-S. Yooa; T.-G. Lee; H.-Y. Choc; Y.-H. Kimd; W.-G. Kima; FEBS Letters, 2005, 579, 5157–5162

V. Aparna; V. Dileep; P. K. Mandal; P. Karthe; C. Sadasivan; M. Haridas; Chem. Biol. Drug Des., 2012, 80, 434–439

A. J. Eastman; R. E. Moore; S. D. Townsend; J. A. Gaddy; D. M. Aronoff; Clin. Ther., 2021, 43, 265–278

L. I. Virchea; F. G. Gligor; A. Frum; M. Mironescu; N. I. Myachikova; C. Georgescu; BIO Web of Conferences, 2021, 40, 1–6

S. Miraj; Rafieian-Kopaei; S. Kiani; J. Evid.-Based Complementary Altern. Med., 2017, 22, 385–394

J. Jaimez Ordaz; J. Martínez Hernánde; J. Ramírez-Godínez; A. Castañeda-Ovando; L. G. González-Olivares; E. Contreras-López; Arch. Latinoam. Nutr., 2018, 68, 268–279

N. Dobros; K. Zawada; K. Paradowska; Antioxidants (Basel), 2022, 11, 1–16

R. Tundis; F. Grande; M. A. Occhiuzzi; V. Sicari; M. R. Loizzo; A. R. Cappello; J. Enzyme Inhib. Med. Chem., 2023, 38, 1–21

S. Özderin; ACU J. For. Fac., 2022, 23, 96–101

G. I. Marovska; I. P. Hambarliyska; N. T. Petkova; I. G. Ivanov; I. N. Vasileva;

A. M. Slavov; Philipp J. Sci., 2023, 152, 861–870

A. Przybylska-Balcerek; T. Szablewski; L. Szwajkowska-Michałek; D. Swierk;

R. Cegielska-Radziejewska; Z. Krejpcio; E. Suchowilska; L. Tomczyk, K. Stuper-Szablewska; Molecules, 2021, 26, 1–17

I. Osorio-Paz; X. Valle-Jiménez; R. Brunauer; S. Alavez; J. Gerontol. Biol. Sci. Med. Sci., 2023, 78, 1100–1107

B. Salehi; L. Monzote; J. Sharifi-Rad; S. M. Ezzat; M. A. Salem; R. M. Merghany; N. M. El Mahdy; C. S. Kılıç; O. Sytar; M. Sharifi-Rad; F. Sharopov; N. Martins; M. Martorell; W. C. Cho; ACS Omega, 2020, 5, 11849–11872

E. Durukan; Prog. Nutr., 2020, 22, 265–274

I. Ciotlaus; A. Balea; M. Pojar-Fenesan; Rev. Chim. (Bucharest), 2020, 71, 136–144

M. Filip; L. Silaghi-Dumitrescu; D. Prodan; C. Sarosi; M. Moldovan; I. Cojocaru; Key Eng. Mater. 2017, 752, 24–28.

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2024-03-30

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CIOTLĂUȘ, I., BALEA, A., POJAR-FENEȘAN, M., FILIP, M. R., & VLASSA, M. (2024). Gc-Ms and Hplc Chromatographic Profile of Majority Volatile and Phenolic Compounds of Some Medicinal Plants From Romania. Studia Universitatis Babeș-Bolyai Chemia, 69(1), 121–145. https://doi.org/10.24193/subbchem.2024.1.08

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