NANOCOMPOSITE BASED ON HYDROXYAPATITE AND SILVER WITH ANTIBACTERIAL ACTIVITY

Authors

  • Aurora MOCANU Research Center of Physical Chemistry, Faculty of Chemistry and Chemical Engineering, Babeş-Bolyai University, Cluj-Napoca, Romania. Email: aurora.mocanu@ubbcluj.ro. https://orcid.org/0000-0002-8728-045X
  • Diana Alexandra FLOREA Department of Chemical Engineering, Faculty of Chemistry and Chemical Engineering, Babeş-Bolyai University, Cluj-Napoca, Romania. Email: diana_florea03@yahoo.com. https://orcid.org/0000-0003-4054-972X
  • Gheorghe TOMOAIA Department of Orthopedics and Traumatology, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca; Academy of Romanian Scientists, Bucharest, Romania. Email: tomoaia2000@yahoo.com. https://orcid.org/0000-0002-5633-6895
  • Lucian-Cristian POP Research Center of Physical Chemistry, Faculty of Chemistry and Chemical Engineering, Babeş-Bolyai University, Cluj-Napoca, Romania. Email: lucian.pop@ubbcluj.ro. https://orcid.org/0000-0002-1778-9226
  • Ancuta DANISTEAN Research Center of Physical Chemistry, Faculty of Chemistry and Chemical Engineering, Babeş-Bolyai University, Cluj-Napoca, Romania. Corresponding author: maria.tomoaia@ubbcluj.ro.
  • Sorin RAPUNTEAN Faculty of Veterinary Medicine, University of Agricultural Sciences and Veterinary Medicine, Cluj-Napoca, Romania. Email: sorin.rapuntean@usamvcluj.ro.
  • Ossi HOROVITZ Research Center of Physical Chemistry, Faculty of Chemistry and Chemical Engineering, Babeş-Bolyai University, Cluj-Napoca, Romania. Corresponding author: maria.tomoaia@ubbcluj.ro. https://orcid.org/0000-0002-3652-8558
  • Maria TOMOAIA-COTISEL Research Center of Physical Chemistry, Faculty of Chemistry and Chemical Engineering, Babeş-Bolyai University, Cluj-Napoca, Romania. Email: maria.tomoaia@ubbcluj.ro. https://orcid.org/0000-0002-0995-3006

DOI:

https://doi.org/10.24193/subbchem.2023.3.01

Keywords:

hydroxyapatite, silver nanoparticles, nanocomposite, antibacterial activity, pathogens

Abstract

A nanocomposite made from hydroxyapatite (HAP) and silver nanoparticles (AgNPs), namely HAP-4.5 wt% AgNPs, is reported. HAP was prepared using a wet precipitation technique, and AgNPs were made by reducing silver nitrate with glucose in basic medium. HAP, AgNPs and HAP-4.5 wt% AgNPs composite were characterized by X-ray diffraction (XRD), SEM - energy dispersive X-ray spectroscopy (EDS) and different imagistic methods: TEM and AFM. The antibacterial effect of the HAP-4.5 wt% AgNPs nanocomposite was tested using diffusion technique in nutritive agar on two pathogenic species, one Gram-negative (Salmonella typhimurium) and one Gram-positive (Bacillus cereus) and promising results were obtained. This hydroxyapatite-silver nanocomposite can be employed as a potential antimicrobial coating for dental and orthopedic implants, or they can be utilized such as bone cements in clinical procedures.

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Published

2023-09-25

How to Cite

MOCANU, A. ., FLOREA, D. A. ., TOMOAIA, G. ., POP, L.-C. ., DANISTEAN, A. ., RAPUNTEAN, S. ., … TOMOAIA-COTISEL, M. . (2023). NANOCOMPOSITE BASED ON HYDROXYAPATITE AND SILVER WITH ANTIBACTERIAL ACTIVITY. Studia Universitatis Babeș-Bolyai Chemia, 68(3), 7–18. https://doi.org/10.24193/subbchem.2023.3.01

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