THE PHENOLIC COMPOUNDS, ANTIOXIDANT AND ANTICHOLINESTERASE ACTIVITIES OF CYCLOTRICHIUM ORIGANIFOLIUM (LABILL.) MANDEN & SCHENG AND THYMUS SIPYLEUS BOISS TEAS FROM TURKEY
DOI:
https://doi.org/10.24193/subbchem.2019.3.18Keywords:
Cyclotrichium origanifolium; Thymus sipyleus; phenolics; anticholinesterase; antioxidantAbstract
In this study, phenolic compounds, antioxidant and anticholinesterase activities of Cyclotrichium origanifolium (Labill.) Manden & Scheng and Thymus sipyleus Boiss teas were investigated. Two methods were used for the preparation of the teas: infusion and decoction. The quantitative amounts of the phenolic contents were determined by LC-MS/MS. Anticholinesterase activity was measured by Ellman method. Also, the antioxidant activity of the tea samples was determined by three methods: 2,2-diphenyl-1-picrylhydrazyl (DPPH) free radical scavenging, β-carotene linoleic acid and CUPRAC assays. Flavonoids and derivatives were the most abundant components of the C. origanifolium and T. sipyleus teas. The infusion of C. origanifolium and decoction of T. sipyleus were found to be rich in phenolics. The tea samples exhibited beneficial antioxidant and anticholinesterase activities. There is a useful relationship between the antioxidant capacity and polyphenolic composition of the decoction and infusion of C. origanifolium and T. sipyleus. This study supported that C. origanifolium and T. sipyleus used as tea traditionally, are a source of natural antioxidant.
References
P.H. Davis; Flora of Turkey and the East Aegean Islands, 7th ed. London, Edinburgh University Press, 1982.
P.H. Davis; R.R. Mill; K. Tan; Flora of Turkey and the East Aegean Islands, 10th ed. London, Edinburgh University Press, 1988.
F. Satıl; A. Kaya; T. Dirmenci; Nord. J. Bot., 2011, 29, 38-48.
K.H. C. Baser; N. Kirimer; G. Tümen; J. Essent. Oil. Res., 1998, 10, 1-8.
A. Gökbulut; Trop. J. Pharm. Res., 2015, 14,1871-1877.
T. Kilic; A. Karahan; T. Dirmenci; T. Arabaci; E. Kocabas; A.C. Goren; Chem. Nat. Compd., 2007, 43, 733-735.
S. Aslan; M. Firat; B. Konuklugil; Chem. Nat. Compd., 2007, 43, 724-725.
A. Alim; I. Goze; A. Cetin; A.D. Atas; N. Vural; E. Donmez; Afr. J. Microbiol. Res., 2009, 3, 422-425.
K.H.C. Baser; B. Demirci; F. Demirci; N. Kirimer; I.C. Hedge; Chem. Nat. Compd., 2001, 37, 336-338.
K.H.C. Baser; S. Sarikardasoglu; G. Tümen; J. Essent. Oil Res., 1994, 6, 9-12.
B. Tepe; M. Sokmen; A. Sokmen; D. Daferera; M. Polissiou; J. Food Eng., 2005, 69, 335-342.
K.H.C. Baser; N. Kirimer; M. Kürkçüoglu; T. Özek; G. Tümen; J. Essent. Oil. Res., 1996, 8, 569-570.
B. Tepe; M. Sokmen; H.A. Akpulat; D. Daferera; M. Polissiou; A. Sokmen; J. Food Eng., 2005, 66, 447-454.
F. Demirci; N. Karaca; M. Tekin; B. Demirci; Microb. Pathog., 2018, 122, 117-121.
C. Ballester-Costa; E. Sendra; J. Fernández-López; J.A. Pérez-Álvarez; M. Viuda-Martos; Ind. Crop. Prod., 2013, 50, 304-311.
K.H.C. Baser; M. Kürkçüoglu; T. Özek; G. Tümen; A. Akgül; J. Essent. Oil Res., 1995, 7, 411-413.
R.S. Gokturk; O. Sagdic; G. Ozkan; O. Unal; A. Aksoy; S. Albayrak; M.Z. Durak et al. J. Essent. Oil Bear. Pl., 2013, 16, 795-805.
G. Yilmaz; I. Telci; N. Kandemir; N. Kaya; Asian J. Chem., 2004, 16, 841.
U. Özgen; A. Mavi; Z. Terzi; C. Kazaz; A. Asçi; Y. Kaya; H. Seçen; Rec. Nat. Prod., 2011, 5, 12.
A. Guzel; H. Aksit; M. Elmastas; R. Erenler; Phcog. Mag., 2017, 13, 316.
I. Gulcin; A.Z. Tel; E. Kirecci; Int. J. Food Prop., 2008,11, 450-471.
A. Ozdemir; M. Yildiz; F.S. Senol; Y. D. Şimay; B. Ibişoglu; A.Gokbulut; I.E. Orhan; M. Ark; Food Chem. Toxicol. 2017,109, 898-909.
I. Orhan; F.S. Şenol; A.R. Gülpinar; M. Kartal; N. Şekeroglu; M. Deveci; K. Kan; B. Şener; Food Chem. Toxicol., 2009, 47, 1304-1310.
S. Emen; B. Çeken; G. Kızıl; M. Kızıl; Pharm. Biol., 2009, 47, 219-229.
F.S. Senol; I.E. Orhan; U. Ozgen; G. Renda; G. Bulut; L. Guven; E.S. Karaoglan; H.G. Sevindik; K. Skalicka-Wozniak; U.K. Caliskan; N. Sekeroglu; S. Afr. J. Bot., 2016, 102, 102-109.
Y. Kiselova; D. Ivanova; T. Chervenkov; D. Gerova; B. Galunska; T. Yankova; An International Journal Devoted to Pharmacological and Toxicological Evaluation of Natural Product Derivatives, 2006, 20, 961-965.
E.W.C. Chan; Y.Y. Lim; K.L. Chong; J.B.L. Tan; S.K. Wong; J. Food Comp. Anal., 2010, 23, 185-189.
H.D. Dorman; M. Koşar; K. Kahlos; Y. Holm; R. Hiltunen; J. Agric. Food Chem., 2003, 5116, 4563-4569.
A.T. Mata; C. Proença; A.R. Ferreira; M.L.M. Serralheiro; J.M.F. Nogueira; M.E.M. Araújo; Food Chem., 2007, 104, 510–517.
M. Petersen; M.S. Simmonds; Phytochem., 2003, 62, 121-125.
B. Gullón; T.A. Lú-Chau; M.T. Moreira; J.M. Lema; G. Eibes; Trends Food Sci. Tech., 2017, 67, 220-235.
Q. Lu; M. Hao; W. Wu; N. Zhang; A. T. Isaac; J. Yin; X. Zho; L. Du; X. Yin; Acta Biochim. Pol., 2018, 65, 35-41.
Z. Ozer; J. Turk. Chem. Soc., Sect. A: Chem., 2018, 5, 445-456.
Z. Ozer Sagir; S. Carikci; T. Kilic; A.C. Goren; Int. J. Food Prop., 2017, 20, 2994-3005.
E. Köksal; E. Bursal; I. Gülçin; M. Korkmaz; C. Çağlayan; A.C. Gören; S.H. Alwasel; Int. J. Food Prop., 2017, 20, 514–25.
A. Ertaş; A.C. Gören; N. Haşimi; V. Tolan; U. Kolak; Rec. Nat. Prod., 2015, 9, 105-115.
H.E. Miller; J. Am. Oil Chem. Soc., 1971, 48, 91.
M.S. Blois; Nature, 1958, 181,1199-2000.
R. Apak; K. Güçlü; M. Özyürek; S.E. Karademir; J. Agr. Food Chem., 2004, 52, 7970-7981.
M. Bener; Y. Shen; Z. Xu; R. Apak; Rec. Nat. Prod., 2016, 10, 794–9.
A.C. Goren; G. Bilsel; M. Bilsel; J. Chem. Metrol., 2007, 1, 1-10.
P. Kalin; I. Gulcin; A.C. Goren; Rec. Nat. Prod., 2015, 9, 496-502.
G.L. Ellman; K.D. Courtney; V. Andres; R.M. Featherstone; Biochem. Pharma., 1961, 7, 88-95.
A. Yılmaz; M. Boga; G. Topçu; Rec. Nat. Prod., 2016, 10, 530-541.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2019 Studia Universitatis Babeș-Bolyai Chemia
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
