EVALUATION OF THE LEVEL OF CONTAMINATION WITH PHTHALATES IN DAIRY PRODUCTS FOUND ON THE ROMANIAN MARKET
DOI:
https://doi.org/10.24193/subbchem.2021.4.05Keywords:
phthalates, milk, dairy products, GC-MS.Abstract
Human exposure to phthalates (artificial phthalic acid esters) is ubiquitous because of the widespread use of these chemicals in consumer and industrial products. The aim of this study was to determine the presence and amount of the phthalates in milk and dairy products collected in Romania. Samples were gathered at several stages during the production, primary production (farm), milk collection center and retail level. Six types of phthalates were assessed by gas chromatography with mass spectrum detection (GC-MS, of which only 4 were detected in the samples - di-n-butyl phthalate (DBP), di-2-ethylhexyl phthalate (DEHP), di-n-octyl phthalate (DOP) and dibutylbenzyl phthalate (BBP). The obtained concentrations ranged between 0.060 – 0.298 mg/kg for DEHP, in raw milk samples and 0.038 - 0.173 mg/kg respectively, in commercial milk. DMP and DEP were not detected in any sample. The lowest quantity of phthalates was detected in yogurt with 0.1% fat – 0.042 mg/kg, and the largest amount was recorded in butter with 75% fat – 0.683 mg/kg. The level of total phthalates in all samples analysed did not exceed the maximum permitted limit of 60 mg/kg.
References
D. Amiridou, D. Voutsa, J. Hazard. Mater., 2011, 185, 281
E. L. Bradley, Determination of phthalates in foods and establishing methodology to distinguish their source, 2012, FSA PROJECT C01048, Report FD 10/05
Xu-L. Cao, Compr. Rev. Food Sci. Food Saf., 2010, 9, 21-43
N. Casajuana, S. Lacorte, J. Agric. Food Chem., 2004, 52 (12), 3702-3707
L. Castle, J. Gilbert and T. Eklund., Food Addit. Contam., 1990, 7, 591-596
COMMISSION REGULATION (EU) No 10/2011 of 14 January 2011 on plastic materials and articles intended to come into contact with food, https://eur-lex.europa.eu/legal-content/EN/TXT/PDF/?uri=CELEX:32011R0010&from=EN
National Research Council (US) Committee on the Health Risks of Phthalates. Phthalates and Cumulative Risk Assessment: The Tasks Ahead. Washington (DC): National Academies Press (US); 2008
Gh. Duca, B. Gaina, R. Sturza, Akademos, 2010, 3(18), 96-100
I. Dumitraşcu. Aerul şi Apa: Componente ale Mediului, 2012, p.337
M.A. Farajzadeh, D. Djozan, M.R. Afshar and M.J. Norouzi, J. Sep. Sci., 2012, 35, 742-749
E. Fasano, F. Bono-Blay, T. Cirillo, P. Montuori, S. Lacorte, Food Control, 2012, 27, 132–138
Y.-L. Feng, J. Zhu, R. Sensenstein, Anal. Chim. Acta, 2005, 538, 41-48
T. Fierens, M. Van Holderbeke, H. Willems, S. De Henauw, I. Sioen. Food Chem. Toxicol., 2012, 50, 2945-2953
T. Fierens, M. Van Holderbeke, H. Willems, S. De Henauw, I. Sioen. Environ. Int., 2013, 51, 1-7
J.S. Fisher, Reproduction, 2004, 127, 305-315
H. Fromme, L. Gruber, E. Seckin, U. Raab, S. Zimmermann, M. Kiranoglu. Environ Int, 2011, 37, 715–22
T. C. Jenkins, M. A. McGuire, J. Dairy Sci., 2006, 89, 1302–1310
M. Krejčíková, A. Jarošová. MENDELNET, 2013, 593-596
Z. Li, F. Xue, L. Xu, C. Peng, H. Kuang, T. Ding. J Chromatogr Sci, 2011, 49, 338–43
J. Lin, W. Chen, H. Zhu, C. Wang, J. Dairy Sci., 2015, 98 (12), 8278–8284
M. Miclean, O. Cadar, C. Roman. Studia UBB Chemia, LVII, 1, 2012, pp. 127 – 133
M. A. Mohamed, A. S. Ammar. Am. J. Food Technol., 2008, 3, 341-346
S. M. Rhind, C. E. Kyle, C. Mackie, G. Telfer, Sci. Total Environ., 2005, 383, 70-80
M. Saad, M. Ahmed, Y. Sultan. World J. Pharm. Res. 2015, 4990, 1799-1807
T. Schettler, Int. J. Androl., 2006, 29, 134–139
I. Schiopu, A. Gurzau, E. Gurzau. Wulfenia, 2015, 22, 345-358
M. Sharman, W.A. Read, L. Castle, J. Gilbert. Food Addit. Contam., 1994, 11, 375-385
H. Soyeurt, I. Misztal, N. Gengler, J. Dairy Sci., 2010, 93, 1722–1728
R.O. Sulentic, I. Dumitrascu, N.C. Deziel, A.E. Gurzau. Int. J. Environ. Res. Public Health, 2018, 15, 2109
J. VELÍŠEK, Chemie potravin 3. Tábor: OSSIS, 2002, 343
C.K. Wei, L.C. Fung, M. Pang, MJAS, 2011, 15 (2), 167 – 174
A. Wendi, L. Reed and G. John. Food Addit Contam., 2009, 111(3), 375-385
H. Yan, X. Cheng, B. Liu. J Chromatogr, 2011, 879:2507–12
EFSA Scientific Committee, J.M.B. Baviera, C. Bolognesi, A. Chesson, P.S. Cocconcelli, R. Crebelli, D.M. Gott, K. Grob, E. Lampi, A. Mortensen, G. Rivière, V. Silano, I.‐L. Steffensen, C. Tlustos, H. Van Loveren, L. Vernis and H. Zorn. EFSA Journal, 2019, 17(12), 5838
A. Giuliani, M. Zuccarini, A. Cichelli, H. Khan and M. Reale. Int. J. Environ.Res. Public Health, 2020, 17, 5655
K. MeeKyung, J.Y. Seon, C. Gab-Soo. Food Addit. Contam. Part A Chem. Anal. Control. Expo. Risk Assess. 2009, 26, 134–138
P. A. Przybylińska, M. Wyszowski. Ecol Chem Eng S., 2016, 23(2), 347-356
P.M. Lorz, F.K. Towae, W. Enke, R. Jäckh, N. Bhargava, W. Hillesheim. Phthalic acid and derivatives. In Ullmann’s Encyclopedia of Industrial Chemistry, 7th ed., B. Elvers Eds., Wiley-VCH, Weinheim, Germany, 2007, Volume 27, pp. 132-180
S.E. Root, S. Savagatrup, A.D. Printz, D. Rodriquez, D.J. Lipomi. Chem. Rev. 2017, 117, 6467–6499
E.N. Peters. Plastics: Information and Properties of Polymeric Materials. In Mechanical Engineers' Handbook: Materials and Mechanical Design, 3rd ed.; M. Kutz Eds., 2005, Volume 1, pp. 335-379
I. Notardonato, C. Protano, M. Vitali, B. Bhattacharya and P. Avino. Appl. Sci. 2019, 9, 2945
M. Tankiewicz, E. Olkowska, A. Berg and L. Wolska. Front. Chem., 2020, 7, 928
M.A. Kamrin. J. Toxicol. Environ. Health B: Crit. Rev., 2009, 12, 157–174
A.M. Calafat, X. Ye, M.J. Silva, Z. Kuklenyik, L.L. Needham, Int. J. Androl., 2006, 29, 166–171
P. Ventrice, D. Ventrice, E. Russoa, G. De Sarroa. Environ. Toxicol. Pharmacol., 2013, 36, 88-96
N. Sopheak, R. Sempere, A. Delmont, A. Paluselli, B. Ouddane. Environ. Sci. Technol., 2015, 49, 4019–4035
D. Savoca, M. Arculeo, S. Barreca, S. Buscemi, S. Caracappa, A. Gentile, M.F. Persichetti, A. Pace. Mar. Pollut. Bull., 2018, 127, 165–169
H. Frederiksen, N. E. Skakkebæk, and A. M. Andersson. Mol. Nutr. Food Res., 2007, 51(7), 899–911
S. J. Genuis, S. Beesoon, R. A. Lobo and D. Birkholz. Sci. World J., 2012, 2012, 615068
Y. Wang, H. Zhu, K. Kannan. Toxics. 2019, 7(2), 21
K. Stamatelatou, C. Pakou, G. Lyberatos; Occurrence, Toxicity and Biodegradation of Selected Emerging Priority Pollutants in Municipal Sewage Sludge. In Comprehensive Biotechnology, 3rd ed.; Murray Moo-Young Eds.; Pergamon, 2011, Volume 6, pp. 421-432
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