CARACTERISATION OF ORIGANUM VULGARE EXTRACTS

Authors

  • Sorin HODISAN University of Oradea, Faculty of Informatics and Science, 1st Universitații str., RO-410087, Oradea, Romania https://orcid.org/0000-0001-7359-4602
  • Ramona POP MAGHIAR National College “Mihai Eminescu”, 18 Roman Ciorogariu str., RO-410017, Oradea, Romania
  • Alina GROZE University of Oradea, Faculty of Informatics and Science, 1st Universitații str., RO-410087, Oradea, Romania
  • Mariana GANEA University of Oradea, Faculty of Medicine and Pharmacy, Department of Pharmacy, 1st December Square, RO-410068, Oradea, Romania
  • Oana STANASEL University of Oradea, Faculty of Informatics and Science, 1st Universitații str., RO-410087, Oradea, Romania ostanasel@uoradea.ro

DOI:

https://doi.org/10.24193/subbchem.2022.4.23

Keywords:

Oregano vulgare, antioxidant activity, polyphenols, HPLC, GC-MS

Abstract

Origanum vulgare L., commonly known as oregano, is a woody, rhizomatous perennial plant. Oregano extracts are a complex mixture of different compounds, in which major constituents are terpenes (mono- and sesquiterpenes). The flavor of oregano oil is generally due to the presence of thymol and carvacrol. Carvacrol has multiple properties: antioxidant, antimicrobial, antitumor, antimutagenic, antigenotoxic, analgesic, antispasmodic, anti-inflammatory, angiogenic, antiparasitic, antiplatelet, insecticidal, antihepatotoxic and neuroprotective. The oregano extract was characterized by analyzing, the antioxidant activity, the total polyphenols content (obtaining 2.4 - 3 mg gallic acid/g), the content of phenolic acids and flavonols by HPLC chromatography, the content of carvacrol (21, 29% in essential oil and 19.78% in ethanolic extract) and thymol (2.59% in essential oil and 2.67% in alcoholic extract) by GC-MS chromatography. Oregano extracts were tested for antimicrobial activity against Staphylococcus aureus. The test results demonstrate the significant antimicrobial activity of these preparations.

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Published

2022-12-30

How to Cite

HODISAN, S., POP MAGHIAR, R., GROZE, A., GANEA, M., & STANASEL, O. (2022). CARACTERISATION OF ORIGANUM VULGARE EXTRACTS. Studia Universitatis Babeș-Bolyai Chemia, 67(4), 353–363. https://doi.org/10.24193/subbchem.2022.4.23

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